Treatment strategies and treatment-related adverse events in MG according to the age of onset

Early-onset (EOMG) and late-onset (LOMG) are distinct groups of MG patients. It is unclear if treatment strategies and treatment-related adverse events may differ according to the age of MG onset. This single-center retrospective study includes all MG patients followed at a tertiary center since 200...

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Veröffentlicht in:Frontiers in neurology 2024-03, Vol.15, p.1277420-1277420
Hauptverfasser: Moura, João, Fernandes, Joana, Lima, Maria João, Sousa, Ana Paula, Samões, Raquel, Martins Silva, Ana, Santos, Ernestina
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Sprache:eng
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Zusammenfassung:Early-onset (EOMG) and late-onset (LOMG) are distinct groups of MG patients. It is unclear if treatment strategies and treatment-related adverse events may differ according to the age of MG onset. This single-center retrospective study includes all MG patients followed at a tertiary center since 2007. We reviewed the electronic clinical records. In total, 212 patients were identified, 142 (67.0%) females, with a median disease duration of 10 years. The median age of symptom onset was 42.0 (26.0-64.5) years, with 130 (61.3%) EOMG cases and 82 (38.7%) LOMG. EOMG were more frequently female, had longer disease duration and often more generalized MG (  
ISSN:1664-2295
1664-2295
DOI:10.3389/fneur.2024.1277420