Optimal treatment of tuberous sclerosis complex associated renal angiomyolipomata: a systematic review

Renal angiomyolipomata associated with tuberous sclerosis complex are often bilateral, multiple and progressive. They cause significant morbidity and mortality in older children and adults. Surveillance and pre-emptive treatment reduce this risk. Recent research suggests treatment with mammalian tar...

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Veröffentlicht in:Therapeutic Advances in Urology 2016-08, Vol.8 (4), p.279-290
Hauptverfasser: Bissler, John J., Kingswood, John C.
Format: Artikel
Sprache:eng
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Zusammenfassung:Renal angiomyolipomata associated with tuberous sclerosis complex are often bilateral, multiple and progressive. They cause significant morbidity and mortality in older children and adults. Surveillance and pre-emptive treatment reduce this risk. Recent research suggests treatment with mammalian target of rapamycin inhibitors is better at preventing bleeding, recurrence, and preserving renal function than percutaneous embolization.
ISSN:1756-2872
1756-2880
DOI:10.1177/1756287216641353