Survey of organ‐derived small extracellular vesicles and particles (sEVPs) to identify selective protein markers in mouse serum

Extracellular vesicles and particles (EVPs) are secreted by organs across the body into different circulatory systems, including the bloodstream, and reflect pathophysiologic conditions of the organ. However, the heterogeneity of EVPs in the blood makes it challenging to determine their organ of ori...

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Veröffentlicht in:	Journal of extracellular biology 2023-08, Vol.2 (8), p.n/a
Hauptverfasser:	Abdelmohsen, Kotb, Herman, Allison B., Carr, Angelica E., Henry‐Smith, Charnae’ A., Rossi, Martina, Meng, Qiong, Yang, Jen‐Hao, Tsitsipatis, Dimitrios, Bangura, Alhassan, Munk, Rachel, Martindale, Jennifer L., Nogueras‐Ortiz, Carlos J., Hao, Jon, Gong, Yi, Liu, Yie, Cui, Chang‐Yi, Hartnell, Lisa M., Price, Nathan L., Ferrucci, Luigi, Kapogiannis, Dimitrios, Cabo, Rafael, Gorospe, Myriam
Format:	Artikel
Sprache:	eng
Schlagworte:	aging biofluids biomarker Biomarkers Body fluids Chromatography Exercise exosomes Extracellular vesicles Gastric cancer Heart Kidneys Liver Mass spectrometry MicroRNAs organ‐derived extracellular vesicles and particles Proteins Proteomes proteomics Protons Scientific imaging small EVPs
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Zusammenfassung:	Extracellular vesicles and particles (EVPs) are secreted by organs across the body into different circulatory systems, including the bloodstream, and reflect pathophysiologic conditions of the organ. However, the heterogeneity of EVPs in the blood makes it challenging to determine their organ of origin. We hypothesized that small (s)EVPs (
ISSN:	2768-2811 2768-2811
DOI:	10.1002/jex2.106