Comparison of the effect of 8 weeks of strength training, water exercise and omega 3 consumption on oxidative stress, CRP, glycosylated hemoglobin and blood pressure in diabetic men with peripheral neuropathy

Background: Diabetes leads to complications such as peripheral neuropathy. This study aimed to compare the effect of 8 weeks of resistance training, water training and omega 3 consumption on malondialdehyde (MDA), C Reactive Protein (CRP), glycosylated hemoglobin and blood pressure in diabetic men with peripheral neuropathy. Materials and Methods: This research is a semi-experimental study and its statistical population consisted of diabetic men with peripheral neuropathy. A total of 80 diabetic patients with neuropathy were divided into four groups: omega-3 supplementation, resistance training, water training and control (For eight weeks, 20 people in each group). Results: In terms of glycosylated hemoglobin and blood pressure, there was a significant difference between the control group and the resistance training (P=0.001), water training (P=0.001) and omega-3 (P=0.001) groups. There was a significant difference between resistance training group and omega-3 group (P=0.041) in terms of glycosylated hemoglobin and between water training group and omega-3 group (P=0.004) in terms of blood pressure. In terms of MDA and CRP, there was a significant difference between the control group with the resistance training group (P=0.001) and the water training group (P=0.001) and between the resistance training group and the omega-3 group (P=0.001) and Water exercise group with omega-3 group (P=0.001), also. Conclusion: Resistance exercise and water exercise reduce inflammation and oxidative stress, as well as blood pressure and glycated hemoglobin in people with diabetic neuropathy. But omega-3 alone was effective only on glycosylated blood pressure and hemoglobin.