Caffeine supplement, inflammation, and hepatic function in cirrhotic patients: A randomized, placebo- controlled, clinical trial

Caffeine supplement, inflammation, and hepatic function in cirrhotic patients: A randomized, placebo- controlled, clinical trial

We investigated the possibility of caffeine supplementation for managing the inflammation, and hepatic function in cirrhotic patients. In this randomized, double-blind, placebo-controlled trial, fifty patients with cirrhosis were randomly assigned to receive either caffeine supplement (400 mg), or p...

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Veröffentlicht in:Heliyon 2025-01, Vol.11 (1), p.e41138, Article e41138
Hauptverfasser: Abbas-Hashemi, Seyed Ali, Yari, Zahra, Hatami, Behzad, Anushiravani, Amir, Kolahdoozan, Shadi, Zamanian, Ali, Akbarzadeh, Nadia, Hekmatdoost, Azita
Format: Artikel
Sprache:eng
Schlagworte:
Caffeine
Cirrhosis
Fibrosis
Inflammation
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Zusammenfassung:We investigated the possibility of caffeine supplementation for managing the inflammation, and hepatic function in cirrhotic patients. In this randomized, double-blind, placebo-controlled trial, fifty patients with cirrhosis were randomly assigned to receive either caffeine supplement (400 mg), or placebo for eight weeks. The results indicated a significant decrease in AST, platelets (P = 0.002), and PTT (P 
ISSN:2405-8440
2405-8440
DOI:10.1016/j.heliyon.2024.e41138