Cross design analysis of randomized and observational data - application to continuation rates for a contraceptive intra uterine device containing Levonorgestrel in adolescents and adults

Cross design analysis of randomized and observational data - application to continuation rates for a contraceptive intra uterine device containing Levonorgestrel in adolescents and adults

To combine results from a randomized controlled study (RCT) and an observational study (OS) to evaluate discontinuation rate of a levonorgestrel-containing intrauterine contraceptive device (LNG IUD) in a real-life setting. We included 253 parous and nulliparous women aged 21-40 years from our own p...

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Veröffentlicht in:BMC women's health 2018-11, Vol.18 (1), p.180-180, Article 180
Hauptverfasser: Vaitsiakhovich, Tatsiana, Filonenko, Anna, Lynen, Richard, Endrikat, Jan, Gerlinger, Christoph
Format: Artikel
Sprache:eng
Schlagworte:
Adolescents
Age
Birth control
Confidence intervals
Continuation rates
Cross design syntheses
Dosage and administration
Evidence-based medicine
Forecasts and trends
Health aspects
Health behavior
Intra-uterine device
Intrauterine devices
Levonorgestrel
Methods
Observational studies
Teenagers
Validity
Womens health
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Beschreibung
Zusammenfassung:To combine results from a randomized controlled study (RCT) and an observational study (OS) to evaluate discontinuation rate of a levonorgestrel-containing intrauterine contraceptive device (LNG IUD) in a real-life setting. We included 253 parous and nulliparous women aged 21-40 years from our own phase II RCT. A total of 1607 women of all ages (including adolescents,
ISSN:1472-6874
1472-6874
DOI:10.1186/s12905-018-0674-1