Role of molecular adsorbent recirculating system in methotrexate-induced acute liver failure: a case report and literature review

We describe the case of a 14-year-old girl with osteosarcoma who was treated with high-dose methotrexate (12 g/m ). Twenty-four hours after the infusion, her plasma methotrexate concentration was elevated at 937 μmol/L (normal

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Bibliographische Detailangaben
Veröffentlicht in:	Frontiers in pediatrics 2024, Vol.12, p.1424919
Hauptverfasser:	Corbisier, T, Von Bueren, André O, Breunis, W B, Grazioli, S
Format:	Artikel
Sprache:	eng
Schlagworte:	acute kidney injury acute liver failure case report extracorporeal treatment methotrexate toxicity
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Beschreibung
Zusammenfassung:	We describe the case of a 14-year-old girl with osteosarcoma who was treated with high-dose methotrexate (12 g/m ). Twenty-four hours after the infusion, her plasma methotrexate concentration was elevated at 937 μmol/L (normal
ISSN:	2296-2360 2296-2360
DOI:	10.3389/fped.2024.1424919