One case of coronavirus disease 2019 (COVID-19) in a patient co-infected by HIV with a low CD4+ T-cell count

•Patients who are infected by SARS-Cov-2 and HIV tend to have a longer disease course and slower generation of specific antibodies•For suspected cases of COVID-19, nucleic acid detection, gene sequencing and antibody detection can confirm the diagnosis, respectively•SARS-Cov-2 may damage lymphocytes...

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Veröffentlicht in:International journal of infectious diseases 2020-07, Vol.96, p.148-150
Hauptverfasser: Wang, Maomao, Luo, Limin, Bu, Haiji, Xia, Hu
Format: Artikel
Sprache:eng
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Zusammenfassung:•Patients who are infected by SARS-Cov-2 and HIV tend to have a longer disease course and slower generation of specific antibodies•For suspected cases of COVID-19, nucleic acid detection, gene sequencing and antibody detection can confirm the diagnosis, respectively•SARS-Cov-2 may damage lymphocytes, especially T-lymphocytes, and the immune system is impaired during the period of disease The ongoing outbreak of COVID-19 that began in Wuhan, China, become an emergency of international concern when thousands of people were infected around the world. This study reports a case simultaneously infected by SARS-Cov-2 and HIV, which showed a longer disease course and slower generation of specific antibodies. This case highlights that a co-infection of SARS-Cov-2 and HIV may severely impair the immune system.
ISSN:1201-9712
1878-3511
DOI:10.1016/j.ijid.2020.04.060