Paradoxical Association Between Baseline Apolipoprotein B and Prognosis in Coronary Artery Disease: A 36,460 Chinese Cohort Study

Paradoxical Association Between Baseline Apolipoprotein B and Prognosis in Coronary Artery Disease: A 36,460 Chinese Cohort Study

Apolipoprotein B (ApoB) and low-density lipoprotein cholesterol (LDL-C) were identified targets for blood lipid management among coronary artery disease (CAD) patients. However, previous studies reported an inverse correlation between baseline LDL-C concentration and clinical outcomes. This study ai...

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Veröffentlicht in:Frontiers in cardiovascular medicine 2022-01, Vol.9, p.822626-822626
Hauptverfasser: Li, Huanqiang, Wang, Bo, Mai, Ziling, Yu, Sijia, Zhou, Ziyou, Lu, Hongyu, Lai, Wenguang, Li, Qiang, Yang, Yongquan, Deng, Jingru, Tan, Ning, Chen, Jiyan, Liu, Jin, Liu, Yong, Chen, Shiqun
Format: Artikel
Sprache:eng
Schlagworte:
all-cause mortality
apolipoprotein B
Cardiovascular Medicine
coronary artery disease
long-term prognosis
paradox
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Zusammenfassung:Apolipoprotein B (ApoB) and low-density lipoprotein cholesterol (LDL-C) were identified targets for blood lipid management among coronary artery disease (CAD) patients. However, previous studies reported an inverse correlation between baseline LDL-C concentration and clinical outcomes. This study aims to explore the definite association between baseline ApoB and long-term prognosis. A total of 36,460 CAD patients admitted to Guangdong Provincial People's Hospital were enrolled and categorized into two groups: high ApoB (≥65 mg/dL) group and low ApoB (
ISSN:2297-055X
2297-055X
DOI:10.3389/fcvm.2022.822626