In-vivo imaging of targeting and modulation of depression-relevant circuitry by transcranial direct current stimulation: a randomized clinical trial

In-vivo imaging of targeting and modulation of depression-relevant circuitry by transcranial direct current stimulation: a randomized clinical trial

Recent clinical trials of transcranial direct current stimulation (tDCS) in depression have shown contrasting results. Consequently, we used in-vivo neuroimaging to confirm targeting and modulation of depression-relevant neural circuitry by tDCS. Depressed participants ( N  = 66, Baseline Hamilton D...

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Veröffentlicht in:Translational psychiatry 2021-02, Vol.11 (1), p.138-138, Article 138
Hauptverfasser: Jog, Mayank. S., Kim, Elizabeth, Anderson, Cole, Kubicki, Antoni, Kayathi, Rishikesh, Jann, Kay, Yan, Lirong, Leaver, Amber, Hellemann, Gerhard, Iacoboni, Marco, Woods, Roger P., Wang, Danny J. J., Narr, Katherine L.
Format: Artikel
Sprache:eng
Schlagworte:
59/57
631/378
692/699/476/1414
Behavioral Sciences
Biological Psychology
Magnetic fields
Medicine
Medicine & Public Health
Neurosciences
Pharmacotherapy
Psychiatry
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Zusammenfassung:Recent clinical trials of transcranial direct current stimulation (tDCS) in depression have shown contrasting results. Consequently, we used in-vivo neuroimaging to confirm targeting and modulation of depression-relevant neural circuitry by tDCS. Depressed participants ( N  = 66, Baseline Hamilton Depression Rating Scale (HDRS) 17-item scores ≥14 and
ISSN:2158-3188
2158-3188
DOI:10.1038/s41398-021-01264-3