Association between rs1761667 CD36 polymorphism and risk of stroke in Korean patients with type 2 diabetes

[2] However, there is no study evaluating the effect of CD36 polymorphism in patients with T2DM according to disease duration. [...]the present study evaluates the association between the rs1761667 CD36 single nucleotide polymorphism (SNP) and stroke in Korean patients with T2DM according to disease...

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Veröffentlicht in:Chinese medical journal 2021-10, Vol.134 (19), p.2385-2387
Hauptverfasser: Lee, Dong-Hwa, Won, Gun Woo, Lee, Yong Hee, Shin, Jong Sung, Ku, Eu Jeong, Oh, Tae Keun, Jeon, Hyun Jeong
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Sprache:eng
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Zusammenfassung:[2] However, there is no study evaluating the effect of CD36 polymorphism in patients with T2DM according to disease duration. [...]the present study evaluates the association between the rs1761667 CD36 single nucleotide polymorphism (SNP) and stroke in Korean patients with T2DM according to disease duration. There were differences in clinical characteristics between men and women. [...]the subgroup analysis was performed according to the duration of T2DM and sex. [5] The main limitation of this study is that we did not evaluate direct CD36 expression according to the genotype of CD36 as in other polymorphism studies. Because of the retrospective study design, there was a possibility for recall bias or missing data. [...]the present study demonstrated that the rs1761667 CD36 SNP is associated with stroke in Korean patients with T2DM, especially in male patients with relatively short duration of DM.
ISSN:0366-6999
2542-5641
DOI:10.1097/CM9.0000000000001501