Bile Acid Conjugates with Anticancer Activity: Most Recent Research

The advantages of a treatment modality that combines two or more therapeutic agents in cancer therapy encourages the study of hybrid functional compounds for pharmacological applications. In light of this, we reviewed recent works on hybrid molecules based on bile acids. Due to their biological prop...

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Veröffentlicht in:Molecules (Basel, Switzerland) Switzerland), 2020-12, Vol.26 (1), p.25
Hauptverfasser: Navacchia, Maria Luisa, Marchesi, Elena, Perrone, Daniela
Format: Artikel
Sprache:eng
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Zusammenfassung:The advantages of a treatment modality that combines two or more therapeutic agents in cancer therapy encourages the study of hybrid functional compounds for pharmacological applications. In light of this, we reviewed recent works on hybrid molecules based on bile acids. Due to their biological properties, as well as their different chemical/biochemical reactive moieties, bile acids can be considered very interesting starting molecules for conjugation with natural or synthetic bioactive molecules.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules26010025