X-ray computed tomography in life sciences

Recent developments within micro-computed tomography (μCT) imaging have combined to extend our capacity to image tissue in three (3D) and four (4D) dimensions at micron and sub-micron spatial resolutions, opening the way for virtual histology, live cell imaging, subcellular imaging and correlative m...

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Veröffentlicht in:	BMC biology 2020-02, Vol.18 (1), p.21-21, Article 21
Hauptverfasser:	Rawson, Shelley D, Maksimcuka, Jekaterina, Withers, Philip J, Cartmell, Sarah H
Format:	Artikel
Sprache:	eng
Schlagworte:	3D imaging Animals Biological research Biological Science Disciplines - instrumentation Biological Science Disciplines - methods Calcification CAT scans Computed tomography Correlative microscopy Histology Humans Iodine Laboratories Life sciences Lightsheet Medical imaging equipment Methods Mice Microscopy Phase contrast Rats Review Stains & staining Three dimensional imaging Time Time-lapse tomography Tomography Tomography, X-Ray Computed - methods Transmission electron microscopy X-ray computed tomography X-rays
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Beschreibung
Zusammenfassung:	Recent developments within micro-computed tomography (μCT) imaging have combined to extend our capacity to image tissue in three (3D) and four (4D) dimensions at micron and sub-micron spatial resolutions, opening the way for virtual histology, live cell imaging, subcellular imaging and correlative microscopy. Pivotal to this has been the development of methods to extend the contrast achievable for soft tissue. Herein, we review the new capabilities within the field of life sciences imaging, and consider how future developments in this field could further benefit the life sciences community.
ISSN:	1741-7007 1741-7007
DOI:	10.1186/s12915-020-0753-2