Changes in glucagon‐like peptide 1 and 2 levels in people with obesity after a diet‐induced weight‐loss intervention are related to a specific microbiota signature: A prospective cohort study

[...]we rejected the hypothesis of microbial composition independence among pre- and post-intervention observations from the same patient, which stresses the importance of accounting for a paired data setting in the downstream analysis (results obtained at family taxonomic level, Figure 1B). SEE PDF] Our results lead us to consider that while diet-induced weight loss impacts gut microbiota composition, and the global metabolic regulation of microbial community interactions maintains a balanced ecosystem. [...]our study shows that GLP secretion, which is dependent on body weight and metabolic status, is linked to specific gut microbiota.