Effects of Flavonoids from French Marigold (Florets of Tagetes patula L.) on Acute Inflammation Model
The major components patuletin and patulitrin were isolated from French marigold (florets of Tagetes patula). Patuletin and patulitrin were found to inhibit acute inflammation in mice. Oral administration of patuletin and patulitrin significantly suppressed hind-paw edema induced by carrageenin and...
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Veröffentlicht in: | International journal of inflammation 2013-01, Vol.2013 (2013), p.1-5 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | The major components patuletin and patulitrin were isolated from French marigold (florets of Tagetes patula). Patuletin and patulitrin were found to inhibit acute inflammation in mice. Oral administration of patuletin and patulitrin significantly suppressed hind-paw edema induced by carrageenin and histamine, while topical application of patuletin and patulitrin significantly inhibited ear edema induced by 12-O-tetradecanoylphorbol-13-acetate and arachidonic acid. Thus, oral and topical administration of patuletin and patulitrin inhibited acute inflammation in mice. These results suggest the anti-inflammatory efficacy of French marigold. |
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ISSN: | 2090-8040 2042-0099 2042-0099 |
DOI: | 10.1155/2013/309493 |