Morphological Characteristics of Ruptured Brain Aneurysms: A Systematic Literature Review and Meta‐Analysis

Morphological Characteristics of Ruptured Brain Aneurysms: A Systematic Literature Review and Meta‐Analysis

BackgroundIt is unclear what morphological features of brain aneurysms are better at predicting risk of rupture. We conducted a meta‐analysis to analyze the best morphological determinants of rupture status.MethodsThe Nested Knowledge platform was used to perform a search of articles reporting on an...

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Veröffentlicht in:Stroke: vascular and interventional neurology 2023-03, Vol.3 (2)
Hauptverfasser: Sanchez, Sebastian, Hickerson, Meredith, Patel, Rishi R., Ghazaleh, Dana, Tarchand, Ranita, Paranjape, Geeta S., Pope, Holly, Ortega‐Gutierrez, Santiago, Pederson, John M., Hasan, David, Raghavan, Madhavan L., Samaniego, Edgar A.
Format: Artikel
Sprache:eng
Schlagworte:
Aneurysm
Aneurysms
aspect ratio
ellipticity index
Meta-analysis
Morphology
nonsphericity index
size ratio
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Zusammenfassung:BackgroundIt is unclear what morphological features of brain aneurysms are better at predicting risk of rupture. We conducted a meta‐analysis to analyze the best morphological determinants of rupture status.MethodsThe Nested Knowledge platform was used to perform a search of articles reporting on aneurysm size, aspect ratio (AR), size ratio (SR), ellipticity index, nonsphericity index, and undulation index. The mean differences between ruptured and unruptured aneurysms were used to calculate effect sizes.ResultsA total of 63 studies with 13 025 aneurysms were included: 6966 ruptured aneurysms and 6059 unruptured aneurysms. Ruptured aneurysms had a larger size (P
ISSN:2694-5746
2694-5746
DOI:10.1161/SVIN.122.000707