Study on pathogenity and immunogenous capacity of Fusobacterium necrophorum

The present study is aimed for veterinarians, researchers and sheep, goats and cattle breeders of and presents an effective prophylactic method in the fight with necrobacilar pododermatitis. The pathogenicity and the determination of the minimum lethal dose in mice, facilitated the demonstration of the immunogenic capacity and the protective effect of an inactivated suspension of Fusobacterium necrophorum. Vaccination of sheep and goats against necrobacillosis induced an increase of antibodies with at least 2log2, evidenced by the slow seroagglutination reaction in tubes. The decrease until the disappearance of the cases of necrobacillary pododermatitis in sheep flocks certifies the immunizing efficacy of the vaccine suspension.