Establishment of a human iPSC line, IISHDOi004-A, from a patient with Usher syndrome associated with the mutation c.2276G>T; p.Cys759Phe in the USH2A gene

Establishment of a human iPSC line, IISHDOi004-A, from a patient with Usher syndrome associated with the mutation c.2276G>T; p.Cys759Phe in the USH2A gene

A human iPSC line, IISHDOi004-A, from fibroblasts obtained from a patient with Usher syndrome, harboring a homozygous mutation in the USH2A gene (c.2276G>T; p.Cys759Phe) has been generated. Reprogramming factors Oct3/4, Sox2, Klf4, and c-Myc were delivered using Sendai virus.

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Veröffentlicht in:Stem cell research 2018-08, Vol.31, p.152-156
Hauptverfasser: Zurita-Díaz, Francisco, Ortuño-Costela, María del Carmen, Moreno-Izquierdo, Ana, Galbis, Liliana, Millán, José María, Ayuso, Carmen, Garesse, Rafael, Gallardo, M. Esther
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Sprache:eng
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Zusammenfassung:A human iPSC line, IISHDOi004-A, from fibroblasts obtained from a patient with Usher syndrome, harboring a homozygous mutation in the USH2A gene (c.2276G>T; p.Cys759Phe) has been generated. Reprogramming factors Oct3/4, Sox2, Klf4, and c-Myc were delivered using Sendai virus.
ISSN:1873-5061
1876-7753
DOI:10.1016/j.scr.2018.08.002