Neuronal loss drives differentially expressed protein‐pathways in the PSP globus pallidus

[...]the mitochondrial signal observed in model I is attenuated when accounting for cell-type composition bias. [...]following adjustment for cell-type composition, we find no significantly differentially expressed proteins between PSP and HC. [...]while we consider the study by Jang et al. to be an...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Clinical and Translational Medicine 2023-07, Vol.13 (7), p.e1280-n/a
Hauptverfasser: Dick, Fiona, Johanson, Gard S., Tzoulis, Charalampos
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:[...]the mitochondrial signal observed in model I is attenuated when accounting for cell-type composition bias. [...]following adjustment for cell-type composition, we find no significantly differentially expressed proteins between PSP and HC. [...]while we consider the study by Jang et al. to be an important contribution of novel data to the field, we advocate caution when interpreting the results.
ISSN:2001-1326
2001-1326
DOI:10.1002/ctm2.1280