Transdermal patch of acetylsalicylic acid as an alternative dosage form: A review

As a substitute for traditional systemic administration, many topical treatments have lately evolved. Transdermal drug delivery systems (TDDSs) are the most appealing of these methods due to their low rate of failure, simplicity of distribution, superior efficiency and preference amongst users. TDDS...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Iraqi Journal of Pharmacy 2022-01, Vol.18 (2), p.64-72
Hauptverfasser: Alhamdany, Hayder, Alfahad, Mohanad
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:As a substitute for traditional systemic administration, many topical treatments have lately evolved. Transdermal drug delivery systems (TDDSs) are the most appealing of these methods due to their low rate of failure, simplicity of distribution, superior efficiency and preference amongst users. TDDS has the potential to be useful not just in medicines, but also in the skincare sector, particularly cosmetics. Since this approach means the development of local administration, it can minimize local drug level accumulation and inappropriate drug distribution to regions not primarily tailored by the medication. Aspirin (acetylsalicylic acid) is becoming the preferred choice against which subsequent antiplatelet medicines are measured in terms of lowering the cardiovascular risk while remaining inexpensive. Along with its substantial presystemic metabolism, orally administered acetylsalicylic acid has the potential of gastrointestinal negative impacts albeit at modest dosages and necessitates regular administration. Transdermal administration avoids the gut and would be more practical and healthier for aspirin usage, particularly during repeated doses. The present review highlights general aspects of aspirin primed as a TDDS as an appropriate topical preparation.
ISSN:2664-2522
1680-2594
2664-2522
DOI:10.33899/iphr.2022.170398