Real-World Clinical Outcomes in Belimumab-Treated US African American and Hispanic Patients with Systemic Lupus Erythematosus: A Retrospective, Observational Study

Introduction This analysis aims to describe real-world clinical outcomes in US African American and Hispanic patients with systemic lupus erythematosus (SLE) receiving belimumab. Methods In this post hoc analysis of OBSErve US (GSK Study 117,295) data, patients received intravenous belimumab (10 mg/...

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Veröffentlicht in:	Rheumatology and Therapy 2023-04, Vol.10 (2), p.447-462
Hauptverfasser:	Bell, Christopher F., Chung, Jake, Rubin, Bernard
Format:	Artikel
Sprache:	eng
Schlagworte:	African American ethnicity African Americans Belimumab Clinical outcomes Drug therapy Family Medicine General Practice Hispanic Americans Hispanic ethnicity Hispanic people Internal Medicine Lupus Medicine Medicine & Public Health Monoclonal antibodies Observational studies Original Research Orthopedics Patient outcomes Quality of Life Research Real-world data Rheumatology Systemic lupus erythematosus
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Zusammenfassung:	Introduction This analysis aims to describe real-world clinical outcomes in US African American and Hispanic patients with systemic lupus erythematosus (SLE) receiving belimumab. Methods In this post hoc analysis of OBSErve US (GSK Study 117,295) data, patients received intravenous belimumab (10 mg/kg) over 24 months. Outcomes assessed every 6 months after belimumab initiation (index) included: physician-assessed overall clinical response (worse, no improvement,
ISSN:	2198-6576 2198-6584
DOI:	10.1007/s40744-022-00524-y