Neo-Aplysiatoxin A Isolated from Okinawan Cyanobacterium Moorea Producens

Neo-Aplysiatoxin A Isolated from Okinawan Cyanobacterium Moorea Producens

A new aplysiatoxin derivative, neo-aplysiatoxin A ( ), along with seven known compounds, neo-debromoaplysiatoxin A ( ), dolastatin 3 ( ), lyngbic acid ( ), malyngamide M ( ), hermitamide A ( ), (-)-loliolide ( ), and (+)-epiloliolide ( ), was isolated from the Okinawan cyanobacterium . Their structu...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Molecules (Basel, Switzerland) Switzerland), 2020-01, Vol.25 (3), p.457
Hauptverfasser: Kawaguchi, Mioko, Satake, Masayuki, Zhang, Bo-Tao, Xiao, Yue-Yun, Fukuoka, Masayuki, Uchida, Hajime, Nagai, Hiroshi
Format: Artikel
Sprache:eng
Schlagworte:
Aplysiatoxin
bioactivity
Biological activity
Communication
Cyanobacteria
Cytotoxicity
Kinases
Mass spectrometry
Mass spectroscopy
moorea producens
NMR
Nuclear magnetic resonance
Studies
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A new aplysiatoxin derivative, neo-aplysiatoxin A ( ), along with seven known compounds, neo-debromoaplysiatoxin A ( ), dolastatin 3 ( ), lyngbic acid ( ), malyngamide M ( ), hermitamide A ( ), (-)-loliolide ( ), and (+)-epiloliolide ( ), was isolated from the Okinawan cyanobacterium . Their structures were elucidated on the basis of spectroscopic data, including high-resolution mass spectrometry and nuclear magnetic resonance. The compounds were evaluated for cytotoxic and diatom growth inhibition activities.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules25030457