Peri-operative application of intra-aortic balloon pumping reduced the in-hospital mortality of patients with coronary artery disease and left ventricular dysfunction

To analyze the early outcomes of peri-operative application of intra-aortic balloon pumping (IABP) in coronary artery bypass grafting (CABG), among patients with coronary artery disease (CAD) and left ventricular dysfunction, to provide a clinical basis for the peri-operative use of IABP. A retrospective analysis of 612 patients who received CABG in the hospital between May 1995 and June 2014. Patients were assigned to an IABP or non-IABP group, according to their treatment, and logistic regression analysis was performed to investigate the influence of peri-operative IABP implantation on in-hospital mortality. Further subgroup analysis was performed on patients with severe (ejection fraction [EF] ≤ 35%) and mild (EF = 36-50%) left ventricular dysfunction. Out of 612 included subjects, 78 belonged to the IABP group (12.7%) and 534 to the non-IABP group. Pre-operative left ventricular EF (LVEF) and EuroSCOREII predicted mortality was higher in the IABP group compared with the non-IABP group (P