Gut microbiota influence in type 2 diabetes mellitus (T2DM)

Gut microbiota influence in type 2 diabetes mellitus (T2DM)

A strong and expanding evidence base supports the influence of gut microbiota in human metabolism. Altered glucose homeostasis is associated with altered gut microbiota, and is clearly associated with the development of type 2 diabetes mellitus (T2DM) and associated complications. Understanding the...

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Veröffentlicht in:Gut pathogens 2021-08, Vol.13 (1), p.1-50, Article 50
Hauptverfasser: Cunningham, A. L, Stephens, J. W, Harris, D. A
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers
Body mass index
Dapagliflozin
Development and progression
Dextrose
Diabetes
Diabetes mellitus (non-insulin dependent)
Glucose
Glucose metabolism
Gut microbiota
Homeostasis
Hyperglycemia
Inflammation
Insulin resistance
Intestinal microflora
Liraglutide
Metabolism
Microbiota
Microbiota (Symbiotic organisms)
Pathogenesis
Physiological aspects
Review
Rodents
Type 2 diabetes
Type two diabetes mellitus
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Zusammenfassung:A strong and expanding evidence base supports the influence of gut microbiota in human metabolism. Altered glucose homeostasis is associated with altered gut microbiota, and is clearly associated with the development of type 2 diabetes mellitus (T2DM) and associated complications. Understanding the causal association between gut microbiota and metabolic risk has the potential role of identifying susceptible individuals to allow early targeted intervention.
ISSN:1757-4749
1757-4749
DOI:10.1186/s13099-021-00446-0