Effect of prophylactic ondansetron and/or continuous infusion of phenylephrine on spinal anesthesia-induced hypotension

[3] We do not fully share with the authors the opinion when they stated that the main contributors to hypotension with sympathetic nerve blockade are the decreases in cardiac output and systemic vascular resistance. Studies have proven many years before the publication of the article in question that the typical hemodynamic effects of spinal anesthesia in healthy pregnant women are a decrease in the systemic vascular resistance and a compensatory increase in cardiac output, which might increase again after fetal extraction by cancellation of uterine aortocaval compression syndrome. [...]we really appreciate the authors' initiative to accomplish this work which will certainly help to clarify and animate the debate about spinal anesthesia-induced hypotension as was suggested by meta-analyses.