Innovations in Formulation and Evaluation of Oral Fast Dissolving Film

The most popular and convenient route for the drug administration is oral route with some merits, demerits, and limitations with some paediatric and geriatrics patients as they face difficulty to take solid dosage forms like capsules or compressed tablets that results in improper dosing due to vomit...

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Veröffentlicht in:Eurasian journal of science and engineering (Online) 2024, Vol.9 (2), p.115-130
Hauptverfasser: Rozhan Arif Muhammed, Zainab Yalman, Bushra Rashid Noaman, Sharad Visht, Sarmad Jabbar, Sana Sirwan Salih
Format: Artikel
Sprache:eng
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Zusammenfassung:The most popular and convenient route for the drug administration is oral route with some merits, demerits, and limitations with some paediatric and geriatrics patients as they face difficulty to take solid dosage forms like capsules or compressed tablets that results in improper dosing due to vomit or removal of drug from buccal cavity. Oral fast dissolving films are a good alternate to overcome these difficulties and to deliver the drugs with any these age groups. Fast dissolving oral films are capable of delivering the drug locally and systemically by absorption through buccal mucosa, sublingual route, and oesophagus and finally form the stomach. Oral fast dissolving films offers a convenient way of dosing medication, not only for special groups of the population like paediatric, geriatric, confined to bed patients, patients with mental problems, but also to the general population. The present article review is focused on composition, preparation methods, evaluation and advancements of orally fast dissolving oral films.
ISSN:2414-5629
2414-5602
DOI:10.23918/eajse.v9i2p9