Multimodality findings of sclerosing adenosis on mammography, US, and MRI in Mexican women

Introduction: Sclerosing adenosis is a benign, proliferative breast disease. Few reports of imaging findings exist in the world literature, and none exists in Mexican literature. This study describes the mammography, ultrasound (US), and magnetic resonance imaging (MRI) findings of histopathologically confirmed sclerosing adenosis in Mexican women. Materials and Methods: This retrospective cross-sectional study was conducted in two private medical centers from January 2006 to July 2022. Adult women with a histopathologic diagnosis of sclerosing adenosis and an imaging examination, mammography, breast (US), and/or MRI were included. Results: A total of 169 women with a median age of 47.0 ± 8.4 years were included. Screening was the main indication for the imaging examination (n = 130, 76.9%). Of the 169 patients, 25 (14.8%) had a relative with a history of breast cancer, whereas 23 (13.6%) had a personal history of breast cancer. Mammography was performed on 155 (91.7%) patients. The most common finding was the grouping of amorphous and pleomorphic calcifications (n = 55, 44.7%). Breast US was performed in 147 (86.9%) patients, with an oval, circumscribed, hypoechoic, avascular mass being the most common findings (n = 61,41.5%), followed by architectural distortions (n = 32, 21.8%). Breast MRI was performed in 17 women; non-mass enhancement was the most common finding (n = 8, 47.0%). Conclusion: Our study comprehensively describes sclerosing adenosis multimodality imaging findings with mammography, US, and MRI. We found no specific imaging feature.