Vancomycin-associated linear IgA disease mimicking toxic epidermal necrolysis

Linear IgA dermatosis is a rare subepidermal autoimmune blistering disease characterized by linear deposition of IgA along the basement membrane zone. In the last three decades, many different drugs have been associated with the drug-induced form of the disease, especially vancomycin. We report a ca...

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Veröffentlicht in:Anais brasileiros de dermatología 2016-09, Vol.91 (5 suppl 1), p.35-38
Hauptverfasser: Pereira, Amanda Regio, Moura, Luis Henrique Barbizan de, Pinheiro, Jhonatan Rafael Siqueira, Pasin, Victor Pavan, Enokihara, Milvia Maria Simões E Silva, Porro, Adriana Maria
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Sprache:eng
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Zusammenfassung:Linear IgA dermatosis is a rare subepidermal autoimmune blistering disease characterized by linear deposition of IgA along the basement membrane zone. In the last three decades, many different drugs have been associated with the drug-induced form of the disease, especially vancomycin. We report a case of vancomycin-induced linear IgA disease mimicking toxic epidermal necrolysis. The aim of this work is to emphasize the need to include this differential diagnosis in cases of epidermal detachment and to review the literature on the subject and this specific clinical presentation.
ISSN:0365-0596
1806-4841
1806-4841
0365-0596
DOI:10.1590/abd1806-4841.20164665