OXA-48–Producing Uropathogenic Escherichia coli Sequence Type 127, the Netherlands, 2015–2022

During 2015–2022, a genetic cluster of OXA-48–producing uropathogenic Escherichia coli sequence type 127 spread throughout the Netherlands. The 20 isolates we investigated originated mainly from urine, belonged to Clermont phylotype B2, and carried 18 genes encoding putative uropathogenicity factors...

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Veröffentlicht in:	Emerging infectious diseases 2023-12, Vol.29 (12), p.2563-2565
Hauptverfasser:	Mulder, Marlies, Notermans, Daan W, Wielders, Cornelia C.H, Bos, Jeroen, Witteveen, Sandra, Ganesh, Varisha A, Landman, Fabian, de Haan, Angela, Schneeberger-van der Linden, Caroline, Hendrickx, Antoni P.A
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimicrobial agents Bacterial infections carbapenemase-producing Enterobacterales Causes of Drug resistance E coli Epidemics Escherichia coli Genes Genetic aspects Genomes Health aspects Identification and classification Laboratories Medical research Medicine, Experimental OXA-48 OXA-48–Producing Uropathogenic Oxalic acid Public health Research Letter Sequence Type 127, the Netherlands, 2015–2022 ST127 UPEC Urinary tract diseases Urinary tract infections Urogenital system uropathogenic Escherichia coli
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Beschreibung
Zusammenfassung:	During 2015–2022, a genetic cluster of OXA-48–producing uropathogenic Escherichia coli sequence type 127 spread throughout the Netherlands. The 20 isolates we investigated originated mainly from urine, belonged to Clermont phylotype B2, and carried 18 genes encoding putative uropathogenicity factors. The isolates were susceptible to first-choice antimicrobial drugs for urinary tract infections.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2912.231114