Ionic charge transport between blockages: Sodium cation conduction in freshly excised bulk brain tissue
We analyze the transient-dc and frequency-dependent electrical conductivities between blocking electrodes. We extend this analysis to measurements of ions' transport in freshly excised bulk samples of human brain tissue whose complex cellular structure produces blockages. The associated ionic c...
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Veröffentlicht in: | AIP advances 2015-08, Vol.5 (8), p.087133-087133 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | We analyze the transient-dc and frequency-dependent electrical conductivities between blocking electrodes. We extend this analysis to measurements of ions' transport in freshly excised bulk samples of human brain tissue whose complex cellular structure produces blockages. The associated ionic charge-carrier density and diffusivity are consistent with local values for sodium cations determined non-invasively in brain tissue by MRI (NMR) and diffusion-MRI (spin-echo NMR). The characteristic separation between blockages, about 450 microns, is very much shorter than that found for sodium-doped gel proxies for brain tissue, >1 cm. |
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ISSN: | 2158-3226 2158-3226 |
DOI: | 10.1063/1.4928652 |