Stroke preventing effect of resveratrol isolated from fungi and in vivo activity in male albino rats

The main objective of the study was to analyze the stroke preventing property of resveratrol from Alternaria alternata SK. The endophytic fungus A. alternata SK was isolated from the Brinjal plant. The isolated fungus was characterized based on morphological characters and molecular methods. It was...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of King Saud University. Science 2022-07, Vol.34 (5), p.102074, Article 102074
Hauptverfasser: Abdel-Hadi, Ahmed, Aloyuni, Saleh, Alharbi, Raed, Jahan, Sadaf, Darwish, Omar, Senthilkumar, Subramanian, Palanisamy, Manikanadan, Ismail, Ahmed
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The main objective of the study was to analyze the stroke preventing property of resveratrol from Alternaria alternata SK. The endophytic fungus A. alternata SK was isolated from the Brinjal plant. The isolated fungus was characterized based on morphological characters and molecular methods. It was cultured in submerged cultivation and resveratrol was isolated. The isolated resveratrol was used to test stroke preventing properties using animal model. The experimental male Albino rat fed with resveratrol decreased HDL cholesterol level in serum. The amount of malondialdehyde significantly lower in the cardiac tissues of Albino AD rat treated with resveratrol (P 
ISSN:1018-3647
DOI:10.1016/j.jksus.2022.102074