RED BLOOD INDICES, PLATELET COUNT AND TRANSFERRIN LEVELS IN CELIAC PATIENTS WITH AND WITHOUT TYPE 1 DIABETES MELLITUS IN HYDERABAD, SINDH, PAKISTAN

OBJECTIVE: To analyze the hematological manifestations among celiac disease (CD) and CD with type-1 diabetes mellitus (T1DM) children to aid in differential diagnosis and management of disease. METHODS: This study was conducted at Institute of Biotechnology and Genetic Engineering, University of Sindh, Jamshoro, Pakistan. CD pediatric patients were diagnosed through serological or intestinal biopsy. The individuals were divided into 5 groups (35 each); Control (A), diagnosed cases of CD (B), individuals affected with celiac-like indications (C), T1DM patients with celiac-like symptoms (D) and T1DM patients (E). RESULTS: Mean age of 175 participants was 9.5±1.2 years. Mean hemoglobin level (mg/dl) was 9.1±1.1, 9.03±1.4, 8.64±1.2 and 11.7±1.3 in group-B, group-C, group-D and group-E respectively as compared to 13.02±1.5 in Group-A (p