Characteristics and prognostic factors of COVID-19 among infected cases: a nationwide Tunisian analysis

The outbreak of coronavirus disease (COVID-19) continues to constitute an international public health concern. Few data are available on the duration and prognostic factors of the disease. We aimed to study the recovery time among a Tunisian cohort of COVID-19 confirmed patients and identify the pro...

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Veröffentlicht in:BMC infectious diseases 2021-02, Vol.21 (1), p.140-140, Article 140
Hauptverfasser: Harizi, Chahida, Cherif, Ines, Najar, Nourhene, Osman, Molka, Mallekh, Rym, Ayed, Oumaima Ben, Ayedi, Yosr, Dhaouadi, Sonia, Hchaichi, Aicha, Safer, Mouna, Letaief, Hejer, Bouaziz, Ilhem, Derouiche, Sondes, Gharbi, Donia, Bouabid, Leila, Bougatef, Souha, Ben Salah, Hamida, Fakhfakh, Radhouane, Abid, Salma, Ben Boubaker, Ilhem Boutiba, Chahed, Mohamed Kouni, Ben-Alaya, Nissaf Bouafif
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Sprache:eng
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Zusammenfassung:The outbreak of coronavirus disease (COVID-19) continues to constitute an international public health concern. Few data are available on the duration and prognostic factors of the disease. We aimed to study the recovery time among a Tunisian cohort of COVID-19 confirmed patients and identify the prognostic factors. A retrospective, nationwide study was conducted from March 2 to May 8, 2020, recruiting all patients who were diagnosed with COVID-19, by RT-PCR methods, in Tunisia. Data were collected via phone call interview. Kaplan-Meir Methods and Cox proportional hazards regression models were, respectively, used to study the recovery time and estimate its prognostic factors. One thousand and thirty patients with COVID-19 (aged 43.2 ± 18.2 years, 526 female (51.1%)) were enrolled. Among them 141 (14.8%) were healthcare professionals. Out of 173 patients (17.8%) admitted to the hospital, 47 were admitted in an intensive care unit. Among 827 patients who didn't require specialized care, 55.5% were self-isolated at home, while the rest were in specialized centers. Six hundred and two patients were symptomatic. A total of 634 (61.6%) patients have recovered and 45 (4.4%) patients died. The median duration of illness was estimated to be 31 days (95% CI: [29-32]). Older age (HR = 0.66, CI:[0.46-0.96], P = 0.031) and symptoms (HR = 0.61, CI:[0.43-0.81], P = 0.021) were independently associated with a delay in recovery time. Being a healthcare professional (HR = 1.52, CI: [1.10-2.08], P = 0.011) and patients in home isolation compared to isolation centers (HR = 2.99, CI: [1.85-4.83], P 
ISSN:1471-2334
1471-2334
DOI:10.1186/s12879-021-05844-y