Flow analysis-hydride generation-gas phase derivative molecular absorption spectrophotometric determination of antimony in antileishmanial drugs

In the present work, the development of a method based on the coupling of flow analysis (FA), hydride generation (HG), and derivative molecular absorption spectrophotometry (D-EAM) in gas phase (GP), is described in order to determine total antimony in antileishmanial products. Second derivative ord...

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Veröffentlicht in:Química Nova 2009, Vol.32 (2), p.337-342
Hauptverfasser: Gallignani, Máximo, Brunetto, María del Rosario, Ovalles, Fernando
Format: Artikel
Sprache:eng
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Zusammenfassung:In the present work, the development of a method based on the coupling of flow analysis (FA), hydride generation (HG), and derivative molecular absorption spectrophotometry (D-EAM) in gas phase (GP), is described in order to determine total antimony in antileishmanial products. Second derivative order (D²224nm) of the absorption spectrum (190 - 300 nm) is utilized as measurement criterion. Each one of the parameters involved in the development of the proposed method was examined and optimized. The utilization of the EAM in GP as detection system in a continuous mode instead of atomic absorption spectrometry represents the great potential of the analytic proposal.
ISSN:0100-4042
1678-7064
1678-7064
DOI:10.1590/S0100-40422009000200013