Association between hypertelorism and nonsyndromic oral clefts

Association between hypertelorism and nonsyndromic oral clefts

Hypertelorism is characterized by the increased distance between the orbits, measured from the most medial portion of its inner walls. It represents a signal found in sev eral craniofacial defects, and oral clefts. Nonsyndromic oral clefts (NOC) are the most common orofacial birth defect, occurring...

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Veröffentlicht in:Brazilian journal of oral sciences 2018-11, Vol.17
Hauptverfasser: Luciano Sólia Nasser, Letízia Monteiro de Barros, Daniella Reis Barbosa Martelli, João Vitor Quadros Tonelli, Mário Sérgio Oliveira Swerts, Hercílio Martelli Júnior
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Sprache:eng
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Zusammenfassung:Hypertelorism is characterized by the increased distance between the orbits, measured from the most medial portion of its inner walls. It represents a signal found in sev eral craniofacial defects, and oral clefts. Nonsyndromic oral clefts (NOC) are the most common orofacial birth defect, occurring in 1 in 500-2,500 live births worldwide. NOC is caused by a complex interplay between environ mental exposures and genetic factors.
ISSN:1677-3225