A study of the relationship between serum asprosin levels and MAFLD in a population undergoing physical examination

Asprosin, an adipokine, was recently discovered in 2016. Here, the correlation between asprosin and metabolic-associated fatty liver disease (MAFLD) was examined by quantitatively assessing hepatic steatosis using transient elastography and controlled attenuation parameter (CAP). According to body m...

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Veröffentlicht in:Scientific reports 2024-05, Vol.14 (1), p.11170-11170, Article 11170
Hauptverfasser: Lv, Dan, Wang, Zepu, Meng, Cuiqiao, Li, Yan, Ji, Shuai
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Sprache:eng
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Zusammenfassung:Asprosin, an adipokine, was recently discovered in 2016. Here, the correlation between asprosin and metabolic-associated fatty liver disease (MAFLD) was examined by quantitatively assessing hepatic steatosis using transient elastography and controlled attenuation parameter (CAP). According to body mass index (BMI), 1276 adult participants were enrolled and categorized into three groups: normal, overweight, and obese. The study collected and evaluated serum asprosin levels, general biochemical indices, liver stiffness measure, and CAP via statistical analysis. In both overweight and obese groups, serum asprosin and CAP were greater than in the normal group ( p  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-024-62124-w