Intraretinal Cysts in Macular Hole: A Structure-Function Correlation Based on En Face Imaging

Purpose: To characterize retinal micromorphic changes on en face optical coherence tomography (OCT) and to determine their role in pathogenesis and visual outcomes in macular hole (MH) surgery. Patients and Methods: This is a retrospective, interventional, consecutive case series of 28 eyes undergoi...

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Veröffentlicht in:	Clinical ophthalmology (Auckland, N.Z.) N.Z.), 2021-01, Vol.15, p.2953-2962
Hauptverfasser:	Nair, Unnikrishnan, Sheth, Jay U, Indurkar, Asmita, Soman, Manoj
Format:	Artikel
Sprache:	eng
Schlagworte:	Automation Cysts en face imaging intraretinal cysts macular hole Open source software Original Research Photoreceptors Retina spectral-domain optical coherence tomography Statistical analysis Surgery Surgical outcomes
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Zusammenfassung:	Purpose: To characterize retinal micromorphic changes on en face optical coherence tomography (OCT) and to determine their role in pathogenesis and visual outcomes in macular hole (MH) surgery. Patients and Methods: This is a retrospective, interventional, consecutive case series of 28 eyes undergoing successful MH surgery. Pre- and post-operative en face OCT were manually segmented, and the correlation between parameters such as MH basal diameter and minimal inlet area, area of cyst in inner plexiform layer (IPL) and outer plexiform layer (OPL), percentage of cyst in IPL and OPL, and amount of ellipsoid zone (EZ) defect and external limiting membrane (ELM) defect was performed. Their relationship with visual acuity (VA) outcomes (Group 1: [greater than or equal to]20/60; 14 eyes; Group 2:
ISSN:	1177-5483 1177-5467 1177-5483
DOI:	10.2147/OPTH.S321594