Analysis of risk factors for papillary thyroid carcinoma and the association with thyroid function indicators

This study aims to analyze the relationship between papillary thyroid carcinoma (PTC) and various factors. The study involved two groups-PTC patients and non-PTC controls. We utilized binary logistic regression and Least Absolute Shrinkage and Selection Operator (Lasso) regression for variable selec...

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Veröffentlicht in:	Frontiers in endocrinology (Lausanne) 2024-09, Vol.15, p.1429932
Hauptverfasser:	Liu, Jianning, Feng, Zhuoying, Gao, Ru, Liu, Peng, Meng, Fangang, Fan, Lijun, Liu, Lixiang, Du, Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult BMI Body Mass Index Case-Control Studies Endocrinology Female Humans iodine Iodine - urine Male Middle Aged PTC Risk Factors ROC Curve Thyroid Cancer, Papillary - blood Thyroid Cancer, Papillary - diagnosis Thyroid Cancer, Papillary - epidemiology Thyroid Cancer, Papillary - urine Thyroid Function Tests Thyroid Gland Thyroid Neoplasms - blood Thyroid Neoplasms - diagnosis Thyroid Neoplasms - epidemiology Thyroid Neoplasms - urine Thyrotropin - blood TSH
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Beschreibung
Zusammenfassung:	This study aims to analyze the relationship between papillary thyroid carcinoma (PTC) and various factors. The study involved two groups-PTC patients and non-PTC controls. We utilized binary logistic regression and Least Absolute Shrinkage and Selection Operator (Lasso) regression for variable selection and risk factor analysis. Correlation analysis was performed using Spearman's rank correlation. The diagnostic value of thyroid stimulating hormone (TSH) levels for PTC was assessed using Receiver Operating Characteristic (ROC) curves. PTC patients exhibited higher body mass index (BMI) (23.71 vs. 22.66, p
ISSN:	1664-2392 1664-2392
DOI:	10.3389/fendo.2024.1429932