Primary Adrenal Leiomyosarcoma: a Case Report and Literature Review

Mencoboni M1, Bergaglio M2, Truini M3, Varaldo M4 1Medical Oncology Unit, "Villa Scassi" Hospital, Genova, Italy. 2Medical Oncology Unit, "Villa Scassi" Hospital, Genova, Italy. 3Pathology Unit, "National Cancer Institute", Genova, Italy. 4Urology Unit, "Villa Scassi" Hospital, Genova, Italy. Abstract The case presented here illustrates a 75 year old female patient who underwent surgical resection of a right adrenal mass of uncertain nature. The final histological diagnosis was consistent with leiomyosarcoma arising from the adrenal anatomic site. Primary leiomyosarcoma of the adrenal gland is a very rare malignant mesenchymal neoplasm: to our knowledge, this is only the twelfth case reported in literature. We describe the clinical course and a brief review of clinical and histological features, biologic behaviour, diagnostic approaches and therapeutic strategies.