The relationship of different levels of high iodine and goiter in school children: a meta-analysis

Over the past decade, the phenomenon of high urine iodine (HUI) and high water iodine (HWI) has become more common. But the risk of goiter caused by different levels of HUI and HWI remains unclear. To explore the risk of goiter development caused by HUI and HWI, and compare the risk of goiter development from different levels of high iodine. The Medline, Cochrane library, Embase, China National Knowledge Infrastructure and Wan fang databases were searched for relevant population-based studies investigating the link between high iodine levels and goiter development in mainland China. Three reviewers extracted data from the included studies independently, assessing the prevalence of goiter development due to high iodine. Taking 100 μg/L ≤ UIC