Live Birth Rate in Patients With Premature Ovarian Insufficiency During Long-Term Follow-Up Under Hormone Replacement With or Without Ovarian Stimulation

We analyzed data from 466 patients with premature ovarian insufficiency (POI) who wished to have a biological child and were followed up while undergoing hormone replacement (HR) therapy with or without ovarian stimulation (OS) between April 2014 and December 2020. OS was conducted in 6891 cycles in...

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Veröffentlicht in:	Frontiers in endocrinology (Lausanne) 2021-12, Vol.12, p.795724-795724
Hauptverfasser:	Ishizuka, Bunpei, Furuya, Masataka, Kimura, Machiko, Kamioka, Eri, Kawamura, Kazuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cohort Studies Endocrinology Estrogen Replacement Therapy - methods Estrogen Replacement Therapy - trends Female Follow-Up Studies Humans infertility Infertility, Female - blood Infertility, Female - therapy Live Birth live birth rate Male ovarian stimulation Ovulation Induction - methods Ovulation Induction - trends Pregnancy pregnancy rate premature ovarian insufficiency Primary Ovarian Insufficiency - blood Primary Ovarian Insufficiency - therapy Retrospective Studies Semen Analysis - methods Semen Analysis - trends Time Factors
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Zusammenfassung:	We analyzed data from 466 patients with premature ovarian insufficiency (POI) who wished to have a biological child and were followed up while undergoing hormone replacement (HR) therapy with or without ovarian stimulation (OS) between April 2014 and December 2020. OS was conducted in 6891 cycles in 429 patients (Group OS), whereas only HR (Group HR) was conducted in 1117 cycles in 37 patients. The follicle growth rate was 48.3% (207/429) per patient in Group OS and 5.4% (2/37) in Group HR (p
ISSN:	1664-2392 1664-2392
DOI:	10.3389/fendo.2021.795724