Treatment of polyethylene microplastics degraded by ultraviolet light irradiation causes lysosome-deregulated cell death

Background Microplastics (MPs), plastic particles

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Veröffentlicht in:	Scientific reports 2024-10, Vol.14 (1), p.24008-11, Article 24008
Hauptverfasser:	Manabe, Sota, Haga, Yuya, Tsujino, Hirofumi, Ikuno, Yudai, Asahara, Haruyasu, Higashisaka, Kazuma, Tsutsumi, Yasuo
Format:	Artikel
Sprache:	eng
Schlagworte:	631/80/82 704/172/4081 Animals Apoptosis Apoptosis - drug effects Apoptosis - radiation effects Autophagy Autophagy - drug effects Autophagy - radiation effects Biodegradation Caspase-3 Cell death Cell Death - drug effects Cell Death - radiation effects Cell size Cellular stress response Cytotoxicity Environmental degradation Flow cytometry Humanities and Social Sciences Humans Immunofluorescence Irradiation Lysosome dysregulation Lysosomes Lysosomes - drug effects Lysosomes - metabolism Macrophages Mice Microplastics Microplastics - toxicity Monocytes Mortality multidisciplinary Physicochemical properties Plastic pollution Polyethylene Polyethylene microplastics Polymers RAW 264.7 Cells Science Science (multidisciplinary) Surface degradation of microplastics THP-1 Cells Ultraviolet radiation Ultraviolet Rays - adverse effects Western blotting
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Beschreibung
Zusammenfassung:	Background Microplastics (MPs), plastic particles
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-024-74800-y