Advanced gestational trophoblastic disease: A case report of medical management prior to surgical intervention

Gestational trophoblastic disease (GTD) is a rare developmental form of proliferative trophoblastic tissue. Sparse literature exists regarding the optimal management of patients with advanced GTD, but the definitive treatment is urgent surgical intervention. A 48-year-old woman presented advanced GTD. She was medically managed for hypertension and hyperthyroidism prior to surgical intervention in order to minimize the risk of anesthetic and surgical complications. Advanced GTD is rare. Undetected GTD can result in complications such as thyrotoxicosis, which poses substantial risks in the peri-operative period. Appropriate identification and management of this clinical problem are essential to prevent complications as well as subsequent malignant sequelae. •A rare case of advanced Gestational Trophoblastic Disease is presented•Surgical evacuation was delayed due to concerns of thyrotoxicosis•The patient's hypertension and hyperthyroidism were medically managed