Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA

Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA

We evaluated enterovirus D68 seroprevalence in Kansas City, Missouri, USA, from samples obtained during 2012–2013. Neutralizing antibodies against Fermon and the dominant 2014 Missouri isolate were universally detected. Titers increased with age. Widespread circulation of enterovirus D68 occurred be...

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Veröffentlicht in:Emerging infectious diseases 2019-03, Vol.25 (3), p.585-588
Hauptverfasser: Harrison, Christopher J, Weldon, William C, Pahud, Barbara A, Jackson, Mary Anne, Oberste, M. Steven, Selvarangan, Rangaraj
Format: Artikel
Sprache:eng
Schlagworte:
adults
aged
Analysis
Antibodies
Care and treatment
Child health
children
Dispatch
enterovirus
Enterovirus infections
Epidemiology
EV-D68
neutralizing antibody
Patient outcomes
Respiratory symptoms
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Zusammenfassung:We evaluated enterovirus D68 seroprevalence in Kansas City, Missouri, USA, from samples obtained during 2012–2013. Neutralizing antibodies against Fermon and the dominant 2014 Missouri isolate were universally detected. Titers increased with age. Widespread circulation of enterovirus D68 occurred before the 2014 outbreak. Research is needed to determine a surrogate of protection.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid2503.180960