Shigella Antimicrobial Drug Resistance Mechanisms, 2004-2014

To determine antimicrobial drug resistance mechanisms of Shigella spp., we analyzed 344 isolates collected in Switzerland during 2004-2014. Overall, 78.5% of isolates were multidrug resistant; 10.5% were ciprofloxacin resistant; and 2% harbored mph(A), a plasmid-mediated gene that confers reduced su...

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Veröffentlicht in:	Emerging infectious diseases 2016-06, Vol.22 (6), p.1083-1085
Hauptverfasser:	Nüesch-Inderbinen, Magdalena, Heini, Nicole, Zurfluh, Katrin, Althaus, Denise, Hächler, Herbert, Stephan, Roger
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Anti-Infective Agents - pharmacology Anti-Infective Agents - therapeutic use Antimicrobial Drug Resistance Mechanisms, 2004–2014 antimicrobial treatment cephalosporins Ciprofloxacin Developing countries Dispatch Drug resistance Drug Resistance, Bacterial Drug Resistance, Multiple, Bacterial Dysentery, Bacillary - drug therapy Dysentery, Bacillary - epidemiology Dysentery, Bacillary - history Dysentery, Bacillary - microbiology Genes, Bacterial History, 21st Century Humans Microbial Sensitivity Tests multidrug resistance resistance genes Shigella Shigella - drug effects Shigella - genetics Shigella - isolation & purification Switzerland - epidemiology
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Beschreibung
Zusammenfassung:	To determine antimicrobial drug resistance mechanisms of Shigella spp., we analyzed 344 isolates collected in Switzerland during 2004-2014. Overall, 78.5% of isolates were multidrug resistant; 10.5% were ciprofloxacin resistant; and 2% harbored mph(A), a plasmid-mediated gene that confers reduced susceptibility to azithromycin, a last-resort antimicrobial agent for shigellosis.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2206.152088