SALT CONSUMPTION. КIDNEYS AS THE TARGET ORGAN. РART IV

The paper is focused in the salt consumption effects on renal system during the development and progression of arterial hypertension. The factors facilitating the transformation of normal hemodynamic profile into the hypertensive one are discussed. The author presents the results of experimental and clinical studies which confirm negative effects of excessive salt consumption on the morphology and function of kidneys as the key organ regulating blood pressure levels. These effects are due to both hemodynamic and non-hemodynamic mechanisms of the salt sensitivity phenomenon. The evidence of the low-salt diet effectiveness in the prevention of kidney pathology, as the target organ damage in arterial hypertension, is presented.