Molecular diagnosis and therapy for cutaneous leishmaniasis of a returned traveler from Mexico

Leishmaniasis is prevalent in Southern Europe, the Middle East, India, Africa, and Central and South America. Cutaneous leishmaniasis may spontaneously heal over time without treatment; however, risk of visceral dissemination and the impact of cosmetic defect are important concerns. We report a Case...

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Veröffentlicht in:Journal of microbiology, immunology and infection immunology and infection, 2021-12, Vol.54 (6), p.1154-1158
Hauptverfasser: Tsai, Pei-Hsuan, Chen, Yu-Ting, Liau, Jau-Yu, Huang, Miao-Hui, Hsu, Hong-Ming, Yeong, Eng-Kean, Hung, Chien-Ching
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Sprache:eng
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Zusammenfassung:Leishmaniasis is prevalent in Southern Europe, the Middle East, India, Africa, and Central and South America. Cutaneous leishmaniasis may spontaneously heal over time without treatment; however, risk of visceral dissemination and the impact of cosmetic defect are important concerns. We report a Case of cutaneous leishmaniasis in a patient who ever traveled to Mexico before the onset of a deteriorating wound around the swollen left eyebrow. A diagnosis of infection with Leishmania mexicana was made based on histopathological examination and molecular identification. Systemic treatment with liposomal amphotericin B and ketoconazole were administered with gradual healing of the lesion. Also, this traveler case implicates that the spread of endemic parasitic diseases may be a concealed risk on the public health for Taiwan underlying globalization.
ISSN:1684-1182
1995-9133
DOI:10.1016/j.jmii.2020.07.007