New treatment insights into pancreatic acinar cell carcinoma: case report and literature review

Pancreatic acinar cell carcinoma (PACC) is a rare pancreatic malignancy with unique clinical, molecular, and morphologic features. The long-term survival of patients with PACC is substantially better than that of patients with ductal adenocarcinoma of the pancreas. Surgical resection is considered t...

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Veröffentlicht in:Frontiers in oncology 2023-07, Vol.13, p.1210064-1210064
Hauptverfasser: Zhao, Fangrui, Yang, Dashuai, Xu, Tangpeng, He, Jiahui, Guo, Jin, Li, Xiangpan
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Sprache:eng
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Zusammenfassung:Pancreatic acinar cell carcinoma (PACC) is a rare pancreatic malignancy with unique clinical, molecular, and morphologic features. The long-term survival of patients with PACC is substantially better than that of patients with ductal adenocarcinoma of the pancreas. Surgical resection is considered the first choice for treatment; however, there is no standard treatment option for patients with inoperable disease. The patient with metastatic PACC reported herein survived for more than 5 years with various treatments including chemotherapy, radiotherapy, antiangiogenic therapy and combined immunotherapy.
ISSN:2234-943X
2234-943X
DOI:10.3389/fonc.2023.1210064