Main pathogenetic factors of arterial hypertension in patients with compromised family history

To identify main hemodynamic, renal and electrolytic disturbances in 514 patients with primary arterial hypertension (AH) and AH-compromised family history (172 men, 342 women aged 16-72 years), as well as in 254 patients (91 men, 163 women aged 24-66 years) with АН-free family history, the following procedures were performed at cardiology in-patient department: blood pressure dynamics assessment during antihypertensive therapy, echocardiography, Doppler ultrasound, retinocapillaroscopy, dynamic renoscintigraphy, renal ultrasound, renoradiography, excretory urography, renal artery angiography, renal electrolyte and uroprotein excretion assessment. Inpatients with AH in family history, AH was significantly associated with left ventricular hypertrophy, retinoangiopathy, congenital renal and renovascular malformations, together with renal dysfunction, increased glomerular filtration rate and uroprotein excretion.