Clinical pregnancy following GnRH agonist administration in the luteal phase of fresh or frozen assisted reproductive technology (ART) cycles: Systematic review and meta-analysis

To study if the GnRH agonist administration in luteal phase improves clinical pregnancy rate of fresh and frozen embryo transfer. Also, this meta-analysis compares the treatment effect of luteal GnRH agonist administration between long agonist and antagonist protocols of fresh cycles, and between tw...

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Veröffentlicht in:European journal of obstetrics & gynecology and reproductive biology: X 2019-07, Vol.3, p.100046-100046, Article 100046
Hauptverfasser: Chau, Le Thi Minh, Tu, Duong Khue, Lehert, Philippe, Dung, Do Van, Thanh, Le Quang, Tuan, Vo Minh
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Sprache:eng
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Zusammenfassung:To study if the GnRH agonist administration in luteal phase improves clinical pregnancy rate of fresh and frozen embryo transfer. Also, this meta-analysis compares the treatment effect of luteal GnRH agonist administration between long agonist and antagonist protocols of fresh cycles, and between two types of treatment: fresh and frozen embryo transfers. Systematic review and meta-analysis (registration number CRD42017059152). For the overall 20 studies (5497 patients), clinical pregnancy rate significantly increased in group of GnRH agonist administration compared to control group (RR 1.24, 95% CI 1.14-1.34, p 
ISSN:2590-1613
2590-1613
DOI:10.1016/j.eurox.2019.100046